JING CHEN UNIVERSITY OF GEORGIA SERIES
Every compound displays a series of distinctive changes in frequency, or Raman shifts, that are as unique as a fingerprint. The first component of their two-in-one system uses a technique known as surface enhanced Raman spectroscopy, or SERS, which measures the change in frequency of a laser as it scatters off a compound. Their results appear in the early online edition of the journal Lab on a Chip and were recently presented at the SPIE Defense, Security and Sensing conference. Zhao and his co-authors-doctoral students Jing Chen and Justin Abell and professor Yao-wen Huang of the UGA College of Agricultural and Environmental Sciences-used nanotechnology to combine two well-known techniques and create their new diagnostic test. "The results are unambiguous and quickly give you a high degree of specificity," said senior author Yiping Zhao, professor of physics in the UGA Franklin College of Arts and Sciences and director of the university's Nanoscale Science and Engineering Center. Their results suggest that the same system could be used to detect pathogens and contaminants in biological mixtures such as food, blood, saliva and urine. In a series of studies, the scientists were able to detect compounds such as lactic acid and the protein albumin in highly diluted samples and in mixtures that included dyes and other chemicals. – Using nanoscale materials, researchers at the University of Georgia have developed a single-step method to rapidly and accurately detect viruses, bacteria and chemical contaminants. The instrument, designed and created by the UGA Instrument Shop, is used to deposit silver nanorods 1,000 times finer than the width of a human hair on a chip that can be used to detect viruses, bacteria and chemical contaminants. Image: University of Georgia researchers, left to right, Yao-Wen Huang, Jing Chen, Yiping Zhao and Justin Abell stand in front of an electron beam evaporator at the UGA Nanoscale Science and Engineering Center.
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